174 , 175 Biallelic loss of function mutations in IFT74 were previously reported to induce BBS with a clear phenotype of obesity, polydactyly, retinal dystrophy, and intellectual disability
Clinical trial data shows retatrutide produces greater weight loss than either semaglutide or tirzepatide at their respective maximum doses
In supplement form, it is used by healthy adults to support general wellness, particularly in areas like digestive balance, mobility, and overall tissue function
The rapid card is of same size as a credit card and holds three films on each side
Immortalized cell lines are popular tools to study drug hepatotoxicity because they are cost effective, readily available as cryopreserved cells, can be of human origin and generally show robust proliferation
Acknowledgements This study was supported by Suzhou Municipal Key Core Technology Research Projects (2023SS19) and Youth Excellence Projects of CNNC (CNNC-2020)
